Antioxidant, Antimicrobial and the Phenolic Content of Infusion, Decoction and Methanolic Extracts of Thyme and Rosmarinus Species
| Autor: | Sahar Nouir, Naceur M Hamdi, Amira Zairi, Maher Chaouachi, Ali Mtiraoui, Marwa Bennani, Mounir Trabelsi, Ines Bergaoui |
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| Rok vydání: | 2018 |
| Předmět: |
Staphylococcus aureus
Antifungal Agents Pharmaceutical Science Decoction Aspergillus flavus 02 engineering and technology Microbial Sensitivity Tests Rosmarinus Antioxidants Thymus Plant 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Anti-Infective Agents Phenols Oils Volatile Gallic acid Thymus extract biology Traditional medicine Chemistry Plant Extracts Methanol Aspergillus niger 030206 dentistry 021001 nanoscience & nanotechnology biology.organism_classification Antimicrobial Anti-Bacterial Agents Officinalis Medicine Traditional 0210 nano-technology Biotechnology |
| Zdroj: | Current pharmaceutical biotechnology. 19(7) |
| ISSN: | 1873-4316 |
| Popis: | Background The plant species Rosmarinus officinalis (RO), Thymus algeriensis (TA) and Thymus capitatus (TC) are widely used in traditional medicine in Tunisia. Their bioactivities have been reported before and particularly referred to their essential oils. The main objective of this work was to assess the phytochemical composition, the antioxidant activity, the antibacterial, antifungal, and cytotoxic potential of these 3 plants. Method The High Performance Liquid Chromatography (HPLC), chemical tests and spectrophotometric methods were used for screening, quantification of phytochemicals and for antioxidant activities. Extracts were evaluated for antibacterial potential by the microdilution method. Antifungal activities were tested using the Poisoned food method against: Aspergillus niger and Aspergillus flavus. The cytotoxic potential of the plant extracts was checked using HCT 116 cultures. Results Results revealed that aqueous extracts are not toxic compared to the methanolic extracts. Phenolic compounds were detected and these extracts showed excellent antioxidant activity presenting dose-dependent relationship. For antibacterial potential, all tested strains are more sensitive to Thymus extracts than Rosmarinus extracts. However, for antifungal activities, only Rosmarinus extracts inhibited mycelial growth. HPLC analysis allowed the identification of ten compounds with the abundance of gallic acid. Conclusion This study showed important bioactivities (antioxidant, antimicrobial, and safety potential) of the plant species RO, TA and TC used in traditional medicine. |
| Databáze: | OpenAIRE |
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