The efficacy of intra-articular sodium hyaluronate in patients with reducing displaced disc of the temporomandibular joint
| Autor: | Birgül Özpinar, Gürbüz Çelebi, Murat Pehlivan, Cihat Öztürk, Yesim Akkoc, Ahmet Saracoglu, Simin Hepguler |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual analogue scale Sodium hyaluronate Joint Dislocations Sodium Chloride Placebo Vibration Injections Intra-Articular law.invention Placebos chemistry.chemical_compound Double-Blind Method Randomized controlled trial Facial Pain law Temporomandibular Joint Disc medicine Humans Joint dislocation Hyaluronic Acid Range of Motion Articular General Dentistry Pain Measurement Chi-Square Distribution business.industry Remission Induction Signal Processing Computer-Assisted medicine.disease Temporomandibular joint Surgery Sound Treatment Outcome medicine.anatomical_structure chemistry Female Range of motion business Follow-Up Studies |
| Zdroj: | Journal of Oral Rehabilitation. 29:80-86 |
| ISSN: | 1365-2842 0305-182X |
| Popis: | In this clinical trial, we examined the efficacy of intra-articular hyaluronic acid (HA) treatment in 38 patients with reducing displaced disc of the temporomandibular joint (TMJ). Subjects received two unilateral upper space injections of HA or physiological saline solution with 1 week apart. Efficacy was based on the following measurements: pain and sound intensity of the joint measured by visual analogue scale (VAS), modified Helkimo's clinical dysfunction index and the intensity of joint vibration during opening and closing the mouth measured by accelerometers. These measurements were performed before the first injection and 1 and 6 months after the last injection. In the treatment group (n=19), all measurements improved significantly at month 1 and at month 6 compared with the baseline (P < 0.01). The same measurements, in the placebo group (n=19), did not show any change, except for the pain intensity which improved at month 1 and month 6 (P < 0.05). The change in baseline measurements of all of the efficacy criteria at month 1 and at month 6 in the treatment group was significantly better compared with the change obtained with placebo at the same time intervals. This study demonstrates that intra-articular sodium hyaluronate (Orthovisc) injection into the TMJ is an effective treatment for a reducing displaced disc. |
| Databáze: | OpenAIRE |
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