Liver dysfunction and energy storage mobilization in traíra, Hoplias malabaricus (Teleostei, Erythrinidae) induced by subchronic exposure to toxic cyanobacterial crude extract
| Autor: | Marcelo Gustavo Paulino, Priscila Adriana Rossi, Francine Perri Venturini, Driele Tavares, Marise Margareth Sakuragui, Gilberto Moraes, Ana Paula Terezan, João Batista Fernandes, Alessandra Giani, Marisa Narciso Fernandes |
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| Rok vydání: | 2022 |
| Předmět: |
Microcystins
Liver Diseases Health Toxicology and Mutagenesis Acid Phosphatase Alanine Transaminase Bilirubin General Medicine Complex Mixtures Management Monitoring Policy and Law Alkaline Phosphatase Cyanobacteria Toxicology Lipids Glucose Liver Ammonia Lactates Animals Aspartate Aminotransferases Characiformes Pyruvates Glycogen |
| Zdroj: | Environmental Toxicology. 37:2683-2691 |
| ISSN: | 1522-7278 1520-4081 |
| DOI: | 10.1002/tox.23628 |
| Popis: | Microcystins (MC) are hepatotoxic for organisms. Liver MC accumulation and structural change are intensely studied, but the functional hepatic enzymes and energy metabolism have received little attention. This study investigated the liver and hepatocyte structures and the activity of key hepatic functional enzymes with emphasis on energetic metabolism changes after subchronic fish exposure to cyanobacterial crude extract (CE) containing MC. The Neotropical erythrinid fish, Hoplias malabaricus, were exposed intraperitoneally to CE containing 100 μg MC-LR eq kg |
| Databáze: | OpenAIRE |
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