Evaluation of a New, Rapid and Automated Immunochemiluminometric Assay for the Measurement of Serum Intact Parathyroid Hormone
| Autor: | Peter R. Ebeling, Peter G. Colman, V. P. Michelangeli, Paula Heyma |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male 030213 general clinical medicine medicine.medical_specialty Hypercalcaemia Adolescent Clinical Biochemistry Parathyroid hormone 030209 endocrinology & metabolism Cross Reactions Sensitivity and Specificity Specimen Handling law.invention 03 medical and health sciences 0302 clinical medicine Reference Values law Internal medicine medicine Humans Hypocalcaemia Child Radiometry Aged Chemiluminescence Aged 80 and over Immunoassay Hyperparathyroidism medicine.diagnostic_test Chemistry Anticoagulants Infant General Medicine Middle Aged Immunochemiluminometric Assay medicine.disease Nursing Homes Endocrinology Evaluation Studies as Topic Parathyroid Hormone Child Preschool Luminescent Measurements Female Hyperparathyroidism Secondary Quantitative analysis (chemistry) hormones hormone substitutes and hormone antagonists |
| Zdroj: | Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 34:97-103 |
| ISSN: | 1758-1001 0004-5632 |
| DOI: | 10.1177/000456329703400115 |
| Popis: | The Immulite parathyroid hormone (PTH) immunochemiluminometric assay (ICMA) was evaluated by measuring serum PTH concentrations in 134 volunteers and 251 patients with various diseases affecting bone and mineral metabolism and comparing with those measured by the Nichols Allegro immunoradiometric (IRMA) assay. Although the assays were highly correlated ( r=0·99, P The enhanced sensitivity of the Immulite ICMA intact PTH assay confers an advantage in the diagnosis of both hyper- and hypocalcaemia, while the shorter incubation times, automation and lack of radioactivity are important practical advantages. |
| Databáze: | OpenAIRE |
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