Diagnostic Challenges of Tuberculous Lymphadenitis Using Polymerase Chain Reaction Analysis: A Case Study
| Autor: | Kazuki Shimokawa, Hitoshi Abo, Yasuaki Masaki, Hideaki Furuse, Fumi Kamiseki, Takeshi Tsuda, Kensuke Suzuki, Hirokazu Taniguchi, Masahiko Nakamura, Shin Ishizawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty biology medicine.diagnostic_test business.industry Polymerase chain reaction analysis Case Report General Medicine biology.organism_classification medicine.disease Tuberculous lymphadenitis law.invention lcsh:Infectious and parasitic diseases Mycobacterium tuberculosis medicine.anatomical_structure law Cervical lymph nodes Biopsy medicine lcsh:RC109-216 business Lymph node Polymerase chain reaction Mycobacterium |
| Zdroj: | Case Reports in Infectious Diseases, Vol 2015 (2015) Case Reports in Infectious Diseases |
| ISSN: | 2090-6633 2090-6625 |
| Popis: | This report presents a case of tuberculous lymphadenitis that was difficult to diagnose using polymerase chain reaction analysis. An 80-year-old Japanese female was hospitalized due to swollen cervical lymph nodes. Her lymph node tests revealed paradoxical polymerase chain reaction results. Polymerase chain reaction analysis of two biopsy tissues using the Cobas TaqMan revealed a positive result forMycobacterium aviumand a negative result forMycobacterium tuberculosis. However, polymerase chain reaction analysis of a cultured colony of acid-fast bacteria from biopsy tissue using the Cobas TaqMan and an alternative polymerase chain reaction analysis of biopsy tissue yielded discordant results. The patient was diagnosed as having tuberculous lymphadenitis. She was treated with antitubercular drugs and subsequently had a reduction in cervical lymph node swelling. Polymerase chain reaction analysis is not 100% accurate; hence, its use as a diagnostic tool for mycobacterial infection requires increased attention. |
| Databáze: | OpenAIRE |
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