Current Perspectives in Metastatic Renal Cell Carcinoma Treatment: The Role of Targeted Therapies
| Autor: | M. Balafouta, Vasiliki Michalaki, C. Gennatas, D. Voros |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Oncology
medicine.medical_specialty business.industry Renal cortex medicine.medical_treatment Cell Disease medicine.disease urologic and male genital diseases Asymptomatic Nephrectomy Renal neoplasm medicine.anatomical_structure Renal cell carcinoma Internal medicine medicine In patient medicine.symptom business |
| Zdroj: | Renal Tumor |
| Popis: | Renal cell carcinoma (RCC) accounts for approximately 3% of adult malignancies and close to 90% of all renal neoplasms. Renal cell carcinomas, by definition, are tumors that originate in the renal cortex. These tumors are often asymptomatic, have diverse clinical manifestations, and can be associated with hereditary syndromes. Surgery is the treatment of choice for localized RCC. In localized RCC, partial nephrectomy for small tumors and radical nephrec‐ tomy for larger tumors continue to be the gold standard. Surgical practice has reduced morbidity and has advanced toward more limited and less invasive resection approaches. In addition, cytoreductive nephrectomy is often indicated before embarking on systemic treatment in patients with metastatic disease. |
| Databáze: | OpenAIRE |
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