Early enteral feeding in conservatively managed stage II necrotizing enterocolitis is associated with a reduced risk of catheter-related sepsis
Autor: | Oskar Baenziger, Hans Ulrich Bucher, Jörg Ersch, Barbara Brotschi, Bernhard Frey |
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Přispěvatelé: | University of Zurich, Ersch, Jörg |
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Male
medicine.medical_specialty Pediatrics Time Factors 610 Medicine & health Enteral administration Sepsis Enteral Nutrition Enterocolitis Necrotizing Pregnancy Recurrence Surveys and Questionnaires medicine Humans 2735 Pediatrics Perinatology and Child Health Neonatology Retrospective Studies Enterocolitis business.industry Infant Newborn Obstetrics and Gynecology 2729 Obstetrics and Gynecology Fasting 10027 Clinic for Neonatology medicine.disease digestive system diseases Surgery Parenteral nutrition 10036 Medical Clinic Catheter-Related Infections Bacteremia Pediatrics Perinatology and Child Health Necrotizing enterocolitis Female medicine.symptom business Complication Infant Premature Intestinal Obstruction Switzerland |
Popis: | Aims: To compare the effect of fasting period duration on complication rates in neonates managed conservatively for necrotizing enterocolitis (NEC) Bell stage II. Methods: We conducted a multicenter study to analyze retrospectively multiple data collected by standardized questionnaire on all admissions for NEC between January 2000 and December 2006. NEC was staged using modified Bell criteria. We divided the conservatively managed neonates with NEC Bell stage II into two groups (those fasted for 5 days) and compared the complication rates. Results: Of the 47 conservatively managed neonates Bell stage II, 30 (64%) fasted for 5 days (range 6–16 days). There were no significant differences for any of the patient characteristics analyzed. One (3%) and four (24%) neonates, respectively, developed post-NEC bowel stricture. One (3%) and two neonates (12%) suffered NEC relapse. None and five (29%) neonates developed catheter-related sepsis. Conclusion: Shorter fasting after NEC appears to lower morbidity after the acute phase of the disease. In particular, shorter-fasted neonates have significantly less catheter-related sepsis. We found no benefit in longer fasting. |
Databáze: | OpenAIRE |
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