A Rare but Reversible Cause of Lithium-Induced Bradycardia
| Autor: | Michael Tofano, Aman Sharma, Basma Ataallah, Rana Al-Zakhari, Gregory Haggerty |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Bradycardia
medicine.medical_specialty Lithium (medication) Cardiology electrocardiogram 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine Internal Medicine medicine voltage-gated sodium channels Sinus rhythm Bipolar disorder Psychiatry Cardiotoxicity business.industry General Engineering medicine.disease pacemaker Discontinuation Mood disorders lithium medicine.symptom Thyroid function business 030217 neurology & neurosurgery lithium-induced bradycardia medicine.drug |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.8600 |
| Popis: | Lithium is a well-known medication that has been used for many years to treat mood disorders. One of its side effects is cardiotoxicity, which usually occurs at serum lithium levels > 1.5 mEq/L but rarely occurs when therapeutic levels of lithium are used. Other causes of bradycardia should be eliminated by performing a detailed workup that includes calcium level, thyroid function, and cardiac workup, with consideration of any medication interactions. Lithium-induced bradycardia is reversible upon discontinuation of lithium, but irreversible sinus node can occur and may warrant permanent insertion of a pacemaker to maintain sinus rhythm when long-term lithium therapy is required. Herein, we describe the case of a 42-year-old woman who presented with symptomatic bradycardia. Bipolar disorder was described in her past medical history, and she was receiving lithium therapy. A detailed workup indicated bradycardia secondary to lithium use. Her condition improved after discontinuation of the lithium, and normal sinus rhythm was restored over the next three days. |
| Databáze: | OpenAIRE |
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