Clinical outcomes after unprotected left main coronary artery occlusion: A retrospective multicentre cohort analysis

Autor: Marco Dürig, Diego Arroyo, Marc Bedossa, Philippe Commeau, Stephane Fournier, Olivier Müller, Paul Barragan, Hervé Le Breton, Serban Puricel, Stéphane Cook
Přispěvatelé: Université de Fribourg = University of Fribourg (UNIFR), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], Lausanne University Hospital, Université de Fribourg
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Catheterization and Cardiovascular Interventions
Catheterization and Cardiovascular Interventions, 2023, 101 (4), pp.679-686. ⟨10.1002/ccd.30585⟩
ISSN: 1522-1946
1522-726X
DOI: 10.1002/ccd.30585⟩
Popis: International audience; Aims: Unprotected left main coronary artery (ULMCA) occlusion is a rare and disastrous condition with scarce data on presentation and outcomes. Herein, we report data on patients presenting with acute coronary syndrome due to ULMCA occlusion at four different institutions. Methods: This is an international multicentre observational study. Baseline characteristics were retro- and prospectively collected. Clinical follow-up was prospective. The primary outcome was in-hospital death. Patients surviving the index hospitalization were compared with nonsurvivors to find predictors of survival. Results: The study population consisted of 55 patients. Eight patients (15%) died in the cath lab, and 23 (42%) died in hospital. Three (6%) deaths were noncardiac and due to major bleeding. Thirty-two (58%) patients survived the index hospitalization and were discharged. These patients were followed for a median of 17.5 months during which three cardiac deaths occurred. Repeat revascularization was performed in 25% (n = 8). Overall mortality at maximum follow-up was 47% (n = 26). The only significant predictor for hospital survival was left ventricular ejection fraction (odds ratio [OR]: 1.10 (per 1 point increase); 95% confidence interval [CI]: 1.02–1.19; p = 0.02). Conclusion: ULMCA occlusion carries a high short-term mortality. Patients who survive index hospitalization have similar mortality rates as compared with other st elevation myocardial infarction patients. © 2023 The Authors. Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.
Databáze: OpenAIRE
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