Occupational asthma by Anisakis simplex
| Autor: | Cristina Martínez, José María Vega, Manuel Lombardero, J.M. Martín Santos, F.‐J. Martín Gil, M. L. Arranz, Alicia Armentia, A. Callejo |
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| Rok vydání: | 1998 |
| Předmět: |
Male
Allergy Immunology medicine.disease_cause Immunoglobulin E Anisakis Bronchial Provocation Tests Allergen Immunopathology medicine Immunology and Allergy Animals Humans Poultry Diseases Asthma Skin Tests biology business.industry Anisakis simplex Allergens Middle Aged medicine.disease biology.organism_classification Occupational Diseases Antigens Helminth biology.protein business Occupational asthma Chickens Fish Flour |
| Zdroj: | The Journal of allergy and clinical immunology. 102(5) |
| ISSN: | 0091-6749 |
| Popis: | Background: No cases of occupational asthma caused by the inhalation of antigens from Anisakis simplex have been published. Objective: The purpose of this study was to evaluate the possibility that A simplex can play a role in the asthma experienced by 2 workers when handling fish and fish flour. Methods: Skin prick and bronchial challenge tests with A simplex were performed. We also carried out measurements of specific IgE to A simplex and immunoblotting. Results: Both patients had strong positive skin test responses, challenge test responses, and specific IgE to A simplex. Immunoblotting showed that both patients also had IgE against several bands in the fish flour extract, suggesting contamination by Anisakis allergens. Conclusion: These 2 patients provide evidence for occupational asthma caused by A simplex, based on in vivo and in vitro tests for Anisakis-specific IgE. (J Allergy Clin Immunol 1998;102:831-4.) |
| Databáze: | OpenAIRE |
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