Regulation of myogenesis by environmental hypoxia
| Autor: | Valérie Bello, Thierry Darribère, Michèle Beaudry, Thierry Launay, Magdalena Hidalgo |
|---|---|
| Přispěvatelé: | Signalisation et morphogenèse = Signalling and morphogenesis (LBD-E12), Laboratoire de Biologie du Développement (LBD), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Association Francaise contre les Myopathies [13955], Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_treatment Morphogenesis Signalling Biology Muscle Development Myoblasts 03 medical and health sciences Gene expression medicine Animals Humans Hypoxia [SDV.BDD]Life Sciences [q-bio]/Development Biology Cell growth Myogenesis Growth factor Wnt signaling pathway Cell Biology Hypoxia (medical) Cell Hypoxia Cell biology 030104 developmental biology Gene Expression Regulation Protein Biosynthesis medicine.symptom Intracellular Signal Transduction |
| Zdroj: | Journal of Cell Science Journal of Cell Science, Company of Biologists, 2016, 129 (15), pp.2887-2896. ⟨10.1242/jcs.188904⟩ Journal of Cell Science, 2016, 129 (15), pp.2887-2896. ⟨10.1242/jcs.188904⟩ |
| ISSN: | 0021-9533 1477-9137 |
| DOI: | 10.1242/jcs.188904⟩ |
| Popis: | In aerobic organisms, oxygen is a critical factor for tissue and organ morphogenesis from embryonic development throughout the adult life. It regulates various intracellular pathways involved in cellular metabolism, proliferation, cell survival and fate. Organisms or tissues rapidly respond to changes in oxygen availability by activating complex signalling networks, which culminate in the control of mRNA translation and/or gene expression. This Commentary presents the effects of hypoxia during embryonic development, myoblasts and satellite cell proliferation and differentiation in vertebrates. We also outline the relationship between Notch, Wnt and growth factor signalling pathways, as well as the post-transcriptional regulation of myogenesis under conditions of hypoxia. |
| Databáze: | OpenAIRE |
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