Preliminary Observations on the Histochemistry of the Cell Surface of Carcinoma of the Cervix
| Autor: | E. A. Williams, G. Wiernik, S. Bradbury, R. H. Cowdell |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1970 |
| Předmět: |
Cancer Research
Surface Properties Cell Uterine Cervical Neoplasms Biology Cell membrane Extracellular matrix chemistry.chemical_compound Hyaluronic acid Neuraminic acid medicine Carcinoma Humans Antigens Hyaluronic Acid Histocytochemistry Sulfates Cell Membrane Articles medicine.disease Molecular biology Epithelium medicine.anatomical_structure Oncology chemistry Biochemistry Carcinoma Squamous Cell Immunohistochemistry Female Neuraminic Acids Radium |
| Zdroj: | British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| Popis: | Histochemical studies on the cell surface and intercellular matrix of normal cervical epithelium, and squamous cell carcinomata have shown the mucosubstances present may be symbolized by the descriptive formula: C(G) mucosubstance; B 3.5; A 2.5 (0.6m MgCl2); T; S. This indicates that sulphate groups are absent and that the intercellular matrix and cell coat are rich in hyaluronic and sialic acids or closely related compounds. These may be important in masking the antigenic expression of the tumour cells. We have not been able to detect any alteration in the mucosubstances at 7 days following radium treatment. ImagesFigs. 1-3 |
| Databáze: | OpenAIRE |
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