Hypolipidemic activity of aqueous extract ofWithania coagulans Dunal in albino rats
| Autor: | P. N. Singh, Siva Hemalatha, J. P. N. Chansouria, A. K. Wahi |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Withania coagulans food.ingredient Albinism Hyperlipidemias Withania Biology Pharmacognosy chemistry.chemical_compound food Animals Hypolipidemic Agents Pharmacology Aqueous extract Traditional medicine Plant Extracts Cholesterol Elevated serum cholesterol Water High fat diet biology.organism_classification Animal Feed Dietary Fats Rats Liver Biochemistry chemistry Fruit Female Commiphora Phytotherapy Lipoprotein |
| Zdroj: | Phytotherapy Research. 20:614-617 |
| ISSN: | 1099-1573 0951-418X |
| Popis: | Administration of an aqueous extract of fruits of Withania coagulans (1 g/kg; p.o.) to high fat diet induced hyperlipidemic rats for 7 weeks, significantly reduced elevated serum cholesterol, triglycerides and lipoprotein levels. This drug also showed hypolipidemic activity in triton induced hypercholesterolemia. The histopathological examination of liver tissues of treated hyperlipidemic rats showed comparatively lesser degenerative changes compared with hyperlipidemic controls. The hypolipidemic effect of W. coagulans fruits was found to be comparable to that of an Ayurvedic product containing Commiphora mukkul. |
| Databáze: | OpenAIRE |
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