Comparison of TNF-α and IL-1β Concentrations in Gingival Crevicular Fluid During Early Alignment Stage of Orthodontic Treatment in Adults and Adolescents
| Autor: | Marzieh Karimi Afshar, Alireza Farsinejad, Molook Torabi, Iman Mohammadzadeh, Fereshteh Safarian |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Tooth Movement Techniques business.industry Orthodontics Gingival Crevicular Fluid Age and sex Gastroenterology Maxillary right central incisor Crevicular fluid Age groups Internal medicine Pediatrics Perinatology and Child Health medicine Cytokines Measurement test Gingival sulcus business General Dentistry After treatment Tooth Movement Technique |
| Zdroj: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada, Volume: 20, Article number: e0004, Published: 20 JUL 2020 |
| Popis: | Objective: To compare the levels of TNF- α and IL-1 β in the gingival crevicular fluid (GCF) during early leveling stage of orthodontic treatment. Material and Methods: This study was carried out on 20 orthodontic patients, including 10 teenagers and 10 adults. Before bonding, GCF was collected with a paper strip in gingival sulcus of maxillary right central incisor on the disto labial aspect for 60 seconds, followed by bonding and insertion of initial 14 NiTi archwire. GCF collection was repeated 24 hours, 7 days, and 28 days after bonding. Measurement of TNF- α and IL-1 β levels was done utilizing Enzyme-Linked Immunosorbent Assay (ELISA). Data were analyzed in SPSS using repeated measurement test . Results: Concentration of TNF- α and IL-1 β increased after treatment. There was no significant relationship between TNF- α and IL-1 β concentrations subsequent to bonding in comparison to the baseline. There was no significant relationship in TNF- α and IL-1 β level changes in the two age groups and between males and females . Conclusion: Concentration of TNF- α and IL-1 β increased after treatment. Age and sex had no statically significant effect on the concentration of TNF- α and IL-1 β . |
| Databáze: | OpenAIRE |
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