INTERNATIONAL COLLABORATION IN RENAL TRANSPLANTATION
| Autor: | J.F. Moorhead, J.R Salaman, M. Bewick, G.B. Williams, G.D. Pegrum, R. T. D. Oliver, J.A Sachs, A.D. Barnes, John Hopewell, I.C. Balfour, J.P Blandy, H Festenstein |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Pediatrics
medicine.medical_specialty Time Factors International Cooperation Tissue Banks Histocompatibility Testing Kidney ABO Blood-Group System Graft vs Host Reaction Ischemia ABO blood group system Cadaver Humans Transplantation Homologous Medicine Antigens Kidney transplantation business.industry General Medicine medicine.disease Kidney Transplantation United Kingdom Country of origin Surgery Europe Transplantation Phenotype Histocompatibility Tissue bank business |
| Zdroj: | The Lancet. 298:228-230 |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(71)92570-0 |
| Popis: | Between April, 1970, and June, 1971, 32 cadaveric kidneys were exchanged between centres on the Continent of Europe and the United Kingdom and Eire, primarily on the basis of HL-A matching. 87 % of the kidneys were transplanted into recipients with one or no detectable donor incompatibilities, including 3 " full house ", fourantigen-identical matches. 23 kidneys (72%) are still functioning. The ischaemia-time did not adversely affect the outcome of the transplant. This matching of donors and recipients was better than could be achieved locally within the country of origin, and consisted largely of kidneys of rare HL-A phenotype or commoner HL-A phenotypes when these were associated with less common ABO blood-groups. The results are encouraging and lead to the hope that future exchanges will include all European donors and recipients within a unified collaborative scheme. |
| Databáze: | OpenAIRE |
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