Adhesion molecules facilitate host-pathogen interaction & mediate Mycobacterium tuberculosis pathogenesis
| Autor: | Durga Bisht, Laxman S. Meena |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Host–pathogen interaction 030106 microbiology lcsh:Medicine Review Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Immune system fibronectin Humans Tuberculosis 030212 general & internal medicine Receptor Lipoarabinomannan biology Chemistry Cell adhesion molecule Macrophages Adhesion - fibronectin - fibronectin-binding protein - lipoarabinomannan - macrophages - Mycobacterium tuberculosis - proline glutamic polymorphic CG repetitive sequence lcsh:R General Medicine Adhesion Mycobacterium tuberculosis biology.organism_classification fibronectin-binding protein Cell biology Fibronectin Host-Pathogen Interactions biology.protein Cytokines lipoarabinomannan proline glutamic polymorphic CG repetitive sequence Cell Adhesion Molecules Mycobacterium Signal Transduction |
| Zdroj: | The Indian Journal of Medical Research Indian Journal of Medical Research, Vol 150, Iss 1, Pp 23-32 (2019) |
| ISSN: | 0971-5916 |
| Popis: | Most of the microorganisms display adhesion molecules on their surface which help them to bind and interact with the host cell during infection. Adhesion molecules help mycobacteria to colonize and invade immune system of the host, and also trigger immune response explicated by the host against the infection. Hence, understanding the signalling pathways illustrated by these molecules to enhance our knowledge on mycobacterial survival and persistence inside the host cell is required. Hence, this review was focussed on the role of adhesion molecules and their receptor molecules. The various mechanisms adopted by adhesion molecules to bind with the specific receptors on the host cell and their role in invasion and persistence of mycobacterium inside the host cell are explained. |
| Databáze: | OpenAIRE |
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