mRNA expression of myogenic-adipogenic makers and adipocyte in skeletal muscle of Hanwoo calves at newborn and 6 months of age
| Autor: | Shil Jin, So-Mi Hwang, Eung-Gi Kwon, Jun-Sang Ahn, Bo-Hye Park, Ui-Hyung Kim, Sun-Sick Jang, Ki-Yong Chung, Dong Hun Kang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Veterinary (miscellaneous) adipocytes Peroxisome proliferator-activated receptor adipogenic Biochemistry Genetics and Molecular Biology (miscellaneous) chemistry.chemical_compound Adipocyte Internal medicine Enhancer binding Myosin medicine Myogenin lcsh:SF1-1100 chemistry.chemical_classification Ecology Skeletal muscle hanwoo calves Endocrinology medicine.anatomical_structure chemistry Adipogenesis Hanwoo myogenic Animal Science and Zoology lcsh:Animal culture Food Science Research Article |
| Zdroj: | Journal of Animal Science and Technology, Vol 62, Iss 6, Pp 893-902 (2020) Journal of Animal Science and Technology |
| ISSN: | 2055-0391 2672-0191 |
| Popis: | This study was conducted to compare the mRNA expression levels of myogenic-adipogenic makers in the skeletal muscle and adipocytes formation, body weight, rumen weight, and papilla length on Hanwoo calves at newborn and 6 months of age. Animals used three newborn Hanwoo calves (NC) and three Hanwoo calves 6 months of age (SC). Body weight and rumen weight were significantly increased in SC compared to NC (p < 0.01), and papilla length was longer about 10-fold in SC than NC. Adipocytes was possible to visually identify more adipocytes in SC compared to NC, and were mainly formed around the blood vessels. mRNA expression of myogenin, myosin heavy chain 1 and myosin heavy chain 2A in both longissimus dorsi (LD) and semimembranosus (SM) was found to increase with calves growth (p < 0.01), and it was confirmed that have higher levels of mRNA expression in SM than LD. In LD tissues, the mRNA expression of stearoyl-CoA desaturase (SCD, p < 0.03) and peroxisome proliferator activated receptor γ (PPARγ, p < 0.04) was significantly higher in SC than NC. In SM tissues, mRNA expression levels of SCD (p < 0.02) and CCAAT/enhancer binding protein β (C/EBPβ, p < 0.01) were higher in SC than NC, and also mRNA expression levels of PPARγ increased, but there was no significant difference. Thus, the calves period suggests that it is an important step in the development of the rumen and the myogenesis and adipogenesis. |
| Databáze: | OpenAIRE |
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