Interaction of Salmonella typhi strains with cultured human monocyte-derived macrophages
| Autor: | A A Branstrom, Eric A. Elsinghorst, D R Sizemore, Richard L. Warren, F A Rubin, David L. Hoover, L C Eck |
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| Rok vydání: | 1997 |
| Předmět: |
AIDS Vaccines
Vaccines Synthetic biology Strain (chemistry) Macrophages Ty21a Immunology Virulence Salmonella typhi Vaccines Attenuated biology.organism_classification Microbiology Enterobacteriaceae Virology Monocytes In vitro Infectious Diseases Species Specificity Humans Macrophage Parasitology Bacteria Research Article |
| Zdroj: | Infection and Immunity. 65:309-312 |
| ISSN: | 1098-5522 0019-9567 |
| DOI: | 10.1128/iai.65.1.309-312.1997 |
| Popis: | Human monocyte-derived macrophages (MDM) provided this laboratory with a tool to develop a primary-cell assay for evaluating the relative virulence of newly constructed Salmonella typhi carrier strains. In this study, the interaction with and survival within MDM were compared for delta aroA143-attenuated strains, wild-type virulent strains, and the current oral-vaccine strain, Ty21a. |
| Databáze: | OpenAIRE |
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