Predictors of clinical outcomes in endodontic microsurgery: A systematic review and meta-analysis
Autor: | Sara Beatríz Quijano Guauque, Dairo Javier Marín-Zuluaga, Claudia García-Guerrero, Gerardo Antonio Pineda, Javier L. Niño-Barrera, Nicolás Molano |
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Rok vydání: | 2017 |
Předmět: |
medicine.medical_specialty
Microsurgery MEDLINE Endodontic microsurgery Dentistry Periapical surgery Clinical factors Cochrane Library Endodontics 03 medical and health sciences 0302 clinical medicine medicine General Dentistry Medicine(all) Crestal bone business.industry 030206 dentistry Total variability Confidence interval lcsh:RK1-715 Meta-analysis 030220 oncology & carcinogenesis lcsh:Dentistry business |
Zdroj: | Giornale Italiano di Endodonzia, Vol 31, Iss 1, Pp 2-13 (2017) |
ISSN: | 1121-4171 |
DOI: | 10.1016/j.gien.2017.03.001 |
Popis: | The prevalence of recurrent periapical lesions has been reported between 43 and 65%, endodontic microsurgery (EM) is an alternative treatment option of recurrent periapical lesions. Aim the aim of the present study was to systematically quantify the effects of the association “clinical factors/follow-up period” on EM outcomes. Methodology Two researchers conducted a literature search from 2005 to 2015. Searched databases were MEDLINE, Evidence-based Endodontics, Cochrane Library, EMBASE, LILACS, SCIELO, Trip-Database. Tables of contents of endodontic journals and references listed on retrieved articles were searched as well. A residual heterogeneity test set at 95% confidence interval controlled sample variability of each study. Meta-regression estimated the factor/follow-up period on the outcomes of the ME. Results 1242 articles were identified, 10 of which were included for meta-regression. On average, EM was 84.13% successful when evaluated from 1 to 6 years. The heterogeneity analysis ( P = 0.87) established the total variability of 8% in reference to sample variability. It was determined that a loss of “Crestal Bone Height” >3 mm proportionally predicts, from the second year on, an increased risk of EM failure (OR = 1.33, 90%CI, 1.01–1.77; P = 0.09). Factors such as “retro-filling material” ( P = 0.0002), “presurgical clinical signs” ( P = 0.0116), and “dentinal root defects” ( P = 0.0001) are considered significant risk factors for EM failure without association to time. Conclusions EM could be considered clinically successful over time. The factor “crestal bone height” estimated a predictive and progressive association of healing from the second year on. Different root-end filling materials aside from MTA could be associated with EM failure, without association with follow-up periods. *Registration Code: CRD42015029593, PROSPERO database. |
Databáze: | OpenAIRE |
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