The outcome of ipsilateral hemihepatectomy in mucin-producing bile duct tumors

Autor: Xinwei Yang, Xing-zhou Yan, Meng-Chao Wu, Baohua Zhang, Jue Yang, Feng Shen, Liang Li
Rok vydání: 2013
Předmět:
Male
medicine.medical_specialty
Epidemiology
Clinical Research Design
lcsh:Medicine
Surgical and Invasive Medical Procedures
Gastroenterology and Hepatology
Research and Analysis Methods
Digestive System Procedures
Surgical oncology
medicine
Medicine and Health Sciences
Hepatectomy
Humans
Clinical Epidemiology
lcsh:Science
Aged
Retrospective Studies
Magnetic resonance cholangiopancreatography
Multidisciplinary
medicine.diagnostic_test
Population Biology
business.industry
Bile duct
General surgery
Liver Diseases
lcsh:R
Mucin
Mucins
Biology and Life Sciences
Retrospective cohort study
Intermittent jaundice
Middle Aged
Surgery
Hepatobiliary surgery
Gastrointestinal Tract
medicine.anatomical_structure
Bile Duct Neoplasms
Research Design
Concomitant
lcsh:Q
Female
Neoplasm Recurrence
Local
Anatomy
business
Digestive System
Research Article
Zdroj: PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e92010 (2014)
ISSN: 1932-6203
Popis: Background Mucin-producing bile duct tumors (MPBTs) are unusual, and we present our experience with nine surgically proven cases. Methods Between November 2002 and November 2012, 9 patients with surgically proven MPBTs (including history of relevant hepatobiliary surgery in 6 patients) were encountered. Their clinical, imaging, and surgical findings were reviewed. Results The most common symptom is intermittent jaundice, which occurs in seven patients. The diagnostic specificity was 77.8% by preoperative Magnetic Resonance Cholangiopancreatography (MRCP). All the patients underwent ipsilateral hemihepatectomy or remnant hemihepatectomy, accompanied caudate lobectomy in one case and concomitant Roux-en-Y choledochojejunostomy in four cases. Postoperative course was uneventful. One patient, who had intra-abdominal recurrence 59 months after surgery, was received reoperation without recurrence at the last follow-up. The remaining eight patients were alive without disease recurrence. Conclusion Based on our follow up of 9 cases that were surgically treated for MPBTs, we conclude that ipsilateral hemihepatectomy is a safe surgical procedure with an observed recurrence risk of 11.1% and all long-term survival.
Databáze: OpenAIRE
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