Effects of Long-Term Supplementation of Bovine Colostrum on the Immune System in Young Female Basketball Players. Randomized Trial
| Autor: | Anita Marcinkiewicz, Anna Skarpańska-Stejnborn, Dariusz Maciejewski, Hanna Dziewiecka, Piotr Basta, Ewa Latour, Mirosława Cieślicka, Sławomir Kujawski, Jerzy Trzeciak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
0301 basic medicine Adolescent animal diseases Lymphocyte Physiology Physical exercise lcsh:TX341-641 Basketball Placebo Article Immunoglobulin G law.invention Leukocyte Count Young Adult 03 medical and health sciences 0302 clinical medicine Immune system Randomized controlled trial law physical exercise medicine Animals Humans immunologic Creatine Kinase Nutrition and Dietetics biology business.industry Colostrum 030229 sport sciences bovine colostrum 030104 developmental biology medicine.anatomical_structure athletes Dietary Supplements supplementation biology.protein Cytokines Cattle Female Creatine kinase business sport lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Nutrients, Vol 13, Iss 118, p 118 (2021) Nutrients Volume 13 Issue 1 |
| ISSN: | 2072-6643 |
| Popis: | An intensive physical exercise program could lead to a decrease in immune system function. Effects of long-term supplementation of bovine colostrum on the response of immune function on physical exercise test in athletes were examined. Twenty-seven elite female basketball players (age 16&ndash 19) were randomly assigned to either an experimental group or a control group. Eventually, n = 11 athletes completed intervention in the experimental group (3.2 g bovine colostrum orally twice a day for 24 weeks), while n = 9 athletes in the control group were given a placebo. Before the supplementation, after 3 and 6 months, subjects performed the physical exercise stress test. Before, just after, and 3 h after physical exercise testing, blood was drawn and immune system indicators were examined. Plasma interleukin (IL)-1alpha, IL-2, IL-10, IL-13, tumor necrosis factor (TNF) alpha, creatine kinase (CK MM), immunoglobulin G (IgG), insulin-like growth factor 1 (IGF1), and WBC, lymphocyte (LYM), monocyte (MON), and granulocyte (GRA) were measured. A statistically significant change in IL-10 in response to the exercise program during the supplementation period in both groups was observed (p = 0.01). However, the results of the rest of the comparisons were statistically insignificant (p > 0.05). Contrary to our initial hypothesis, there were no significant effects of bovine supplementation on the dynamics of immune system function indicators. |
| Databáze: | OpenAIRE |
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