Author Correction: Culex pipiens crossing type diversity is governed by an amplified and polymorphic operon of Wolbachia
| Autor: | Manon Bonneau, Martin Cohen-Gonsaud, Mathieu Sicard, Marwa Beji, Fabienne Justy, Célestine M. Atyame, Mylène Weill |
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| Přispěvatelé: | Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement [IRD] : UR226-Centre National de la Recherche Scientifique (CNRS), Processus Infectieux en Milieu Insulaire Tropical (PIMIT), Centre National de la Recherche Scientifique (CNRS)-IRD-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de La Réunion (UR), Laboratoire d’Epidémiologie et de Microbiologie Vétérinaire (LR11IPT03), Institut Pasteur de Tunis, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Tunis El Manar (UTM), Centre de Biochimie Structurale [Montpellier] (CBS), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE), Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IRD-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
0106 biological sciences 0301 basic medicine Science General Physics and Astronomy Type (model theory) 010603 evolutionary biology 01 natural sciences Host Specificity Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Bacterial Proteins Operon medicine Animals Amino Acid Sequence lcsh:Science Author Correction Symbiosis Crosses Genetic Mathematics Confusion Polymorphism Genetic Multidisciplinary Base Sequence Sequence Homology Amino Acid Toxin-Antitoxin Systems General Chemistry Culex Drosophila melanogaster 030104 developmental biology [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology lcsh:Q Female Line (text file) medicine.symptom Sequence Alignment Algorithm Genome Bacterial Wolbachia |
| Zdroj: | Nature Communications Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.1491. ⟨10.1038/s41467-018-03799-4⟩ Nature Communications, 2018, 9 (1), pp.1491. ⟨10.1038/s41467-018-03799-4⟩ Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018) |
| ISSN: | 2041-1723 |
| Popis: | Culex pipiens mosquitoes are infected with Wolbachia (wPip) that cause an important diversity of cytoplasmic incompatibilities (CIs). Functional transgenic studies have implicated the cidA-cidB operon from wPip and its homolog in wMel in CI between infected Drosophila males and uninfected females. However, the genetic basis of the CI diversity induced by different Wolbachia strains was unknown. We show here that the remarkable diversity of CI in the C. pipiens complex is due to the presence, in all tested wPip genomes, of several copies of the cidA-cidB operon, which undergoes diversification through recombination events. In 183 isofemale lines of C. pipiens collected worldwide, specific variations of the cidA-cidB gene repertoires are found to match crossing types. The diversification of cidA-cidB is consistent with the hypothesis of a toxin–antitoxin system in which the gene cidB co-diversifies with the gene cidA, particularly in putative domains of reciprocal interactions. Wolbachia causes cytoplasmic incompatibility (CI) between mosquitoes infected with different strains, but the genetic basis of observed CI diversity is unknown. Here, Bonneau et al. sequence Wolbachia from over 100 Culex pipiens lines and show that crossing types match variations of the toxin-antitoxin cidA-cidB genes. |
| Databáze: | OpenAIRE |
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