Developing the Biomolecular Screening Facility at the EPFL into the Chemical Biology Screening Platform for Switzerland
| Autor: | Gerardo Turcatti |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Engineering
assay development Biomedical Research Systems biology target-based assays Chemical biology Nanotechnology hits-to-leads high-content screening Drug Discovery Applied research RNA Small Interfering Competence (human resources) assay automation Drug discovery business.industry Organic Chemistry Academic screening General Medicine Computer Science Applications Chemical screening High-Throughput Screening Assays Engineering management High-content screening phenoytpic assays Workforce hits prioritization business Chemical genetics Switzerland |
| Zdroj: | Combinatorial chemistryhigh throughput screening. 17(4) |
| ISSN: | 1875-5402 |
| Popis: | The Biomolecular Screening Facility (BSF) is a multidisciplinary laboratory created in 2006 at the Ecole Polytechnique Federale de Lausanne (EPFL) to perform medium and high throughput screening in life sciences-related projects. The BSF was conceived and developed to meet the needs of a wide range of researchers, without privileging a particular biological discipline or therapeutic area. The facility has the necessary infrastructure, multidisciplinary expertise and flexibility to perform large screening programs using small interfering RNAs (siRNAs) and chemical collections in the areas of chemical biology, systems biology and drug discovery. In the framework of the National Centres of Competence in Research (NCCR) Chemical Biology, the BSF is hosting 'ACCESS', the Academic Chemical Screening Platform of Switzerland that provides the scientific community with chemical diversity, screening facilities and know-how in chemical genetics. In addition, the BSF started its own applied research axes that are driven by innovation in thematic areas related to preclinical drug discovery and discovery of bioactive probes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|