Prevalence of SARS-CoV-2 in Patients with Severe Pneumonia in Khuzestan Province, Iran
| Autor: | Maniya Arshadi, Azarakhsh Azaran, Kambiz Ahmadi-Angali, Seyed Saeed Seyedian, Gholamreza Shariati, Farid Yousefi, Farhad Abolnezhadian, Mehdi Parsanahad, Mohammad Rashno, Fatemeh Ahmadi, Niloofar Neisi, Mehran Varnaseri, Gholam Abbas Kaydani, Seyed Mehdi Hosseinizadeh, Homayoun Amiri, Roohangiz Nashibi, Hatam Boostani, Shahram Jalilian, Sasan Moogahi, Seyed Mohammad Alavi, Manoochehr Makvandi, Hooman Keifarrokhi, Shokrolah Salmanzadeh |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Pneumonia Viral lcsh:Medicine Iran Severity of Illness Index Real-time polymerase chain reaction law.invention Young Adult law Internal medicine Lymphopenia Severity of illness Epidemiology Prevalence Immunology and Allergy Medicine Humans Child Lung Polymerase chain reaction Aged Aged 80 and over Nucleocapsid protein business.industry SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lcsh:R Outbreak Respiratory infection COVID-19 Infant Pneumonia Middle Aged medicine.disease respiratory tract diseases Hospitalization medicine.anatomical_structure C-Reactive Protein COVID-19 Nucleic Acid Testing Child Preschool Female business Tomography X-Ray Computed |
| Zdroj: | Iranian Journal of Allergy, Asthma and Immunology, Vol 19, Iss 5 (2020) |
| ISSN: | 1735-5249 1735-1502 |
| Popis: | The emergence of a highly pathogenic virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accounts for severe pneumonia throughout the world. More than 7 million world population have been infected with SARS-CoV-2, and the number of deaths is increasing every day. This study aimed to evaluate the frequency of SARS-CoV-2 in hospitalized patients with acute respiratory infection (ARI). During an outbreak of the SARS-CoV-2, the nasopharyngeal and oropharyngeal swabs were collected from 909 hospitalized patients with severe pneumonia, including 517 (56.9%) males and 392 (43.1%) females. All the collected samples were from different cities of Khuzestan province from 19 February to- 27 March 2020. The RNA was extracted from samples and subjected to real-time polymerase chain reaction (PCR) tests for the detection of the SARS-CoV-2. Simultaneously, the computerized tomography (CT) scan was tested for the presence of ground-glass opacity in the lung among the patients. Of the total number of 909 specimens, 328 (36.08%) cases, including 185 (20.35%) females and 143 (15.73%) males, were positive for the SARS-CoV-2 while, 581 (63.9%) cases, including 374 (41.14%) males and 207 (22.77%) were negative for the SARS-CoV-2 by real-time PCR (p=0.001).Four hundred sixteen (45.76%) cases were positive for ground-glass opacity in the lung by CT scan, while 328/909 (36.08%) trials proved positive for SARS-CoV-2 by the real-time PCR (p=0.003). In this study, 36.08% of patients were positive for SARS-CoV-2. Although the results of positive cases by CT scan showed higher than real-time PCR, screening the SARS-CoV-2 with a real-time PCR method is the first line of choice. |
| Databáze: | OpenAIRE |
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