Comparison of next generation diagnostic systems (NGDS) for the detection of SARS-CoV-2

Autor:	Antonio O. Sanchez, Anna R. Ochoa, Sallie L. Hall, Chet R. Voelker, Rachel E. Mahoney, Jennifer S. McDaniel, August Blackburn, Susana N. Asin, Tony T. Yuan
Rok vydání:	2022
Předmět:	Microbiology (medical) SARS-CoV-2 Biochemistry (medical) Clinical Biochemistry Public Health Environmental and Occupational Health COVID-19 Hematology Sensitivity and Specificity Specimen Handling Medical Laboratory Technology Nasopharynx Immunology and Allergy Humans Saliva
Zdroj:	Journal of clinical laboratory analysis. 36(4)
ISSN:	1098-2825
Popis:	The World Health Organization (WHO) declared coronavirus disease 2019 (COVID-19) a pandemic in March 2020. Initially, supply chain disruptions and increased demand for testing led to shortages of critical laboratory reagents and inadequate testing capacity. Thus, alternative means of biosample collection and testing were essential to overcome these obstacles and reduce viral transmission. This study aimed to 1) compare the sensitivity and specificity of Cepheid GeneXpertA total of 1,080 specimens consisting of nasopharyngeal (NP) swabs in VTM, NP swabs in saline, nasal swabs, oropharyngeal (OP) swabs, and saliva were collected from 216 enrollees. Limit of detection (LoD) assays, NP VTM and NP saline concordance, and saliva testing were performed on the BioFireLoD and comparative testing demonstrated increased sensitivity with the Cepheid compared with the BioFireThe Cepheid and BioFire
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5849a41f04ef4d3345d36ad2862e2914 https://pubmed.ncbi.nlm.nih.gov/35174538 Zobrazit plný text záznamu Plný text