The role of bronchoalveolar lavage in the diagnosis of suspected opportunistic pneumonia
| Autor: | E. H. Tai, P. W. Holmes, C. A. Stone, Michael J. Abramson |
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| Předmět: |
Pathology
medicine.medical_specialty Lung Neoplasms Biopsy Pneumonia Viral Opportunistic Infections Neutropenia Malignancy Bronchoscopy Pneumonia Mycoplasma Internal Medicine medicine Humans Lung Immunodeficiency medicine.diagnostic_test business.industry Pneumonia Pneumocystis Bacterial Infections Pneumonia respiratory system medicine.disease respiratory tract diseases Bronchoalveolar lavage Pneumocystis carinii business Bronchoalveolar Lavage Fluid |
| Zdroj: | Scopus-Elsevier |
| Popis: | We report 50 immunocompromised patients with pulmonary infiltrates who underwent fibreoptic bronchoscopy, including bronchoalveolar lavage, on 56 occasions. The underlying diseases were mostly lymphoma, leukemia, other malignancies and renal failure. The commonest immunodeficiency factors were chemotherapy, steroids and neutropenia. A positive diagnosis could be made from analysis of the bronchoalveolar lavage on 59% (33/56) occasions. This was a comparable yield to transbronchial lung biopsy 57% (16/27), and superior to proximal airways wash 24% (13/55), or bronchial brushings 29% (10/34). Open lung biopsy added additional diagnostic information in three of the four cases in which it was performed. The most common final diagnoses were bacterial, viral or Pneumocystis carinii pneumonia and recurrent malignancy. We conclude that bronchoalveolar lavage is a safe procedure with a high diagnostic yield in the immunocompromised host with suspected opportunistic pneumonia. |
| Databáze: | OpenAIRE |
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