Synchronous Peripancreatic Lymph Node Gastrinoma and Gastric Neuroendocrine Tumor Type 2

Autor: Woon Ki Lee, Keon Kuk Kim, Kwang Ahn Kwon, Sun Jin Sym, Eui Joo Kim, Hee Woo Lee, Jun-Won Chung, Yoon Jae Kim
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Clinical Endoscopy, Vol 49, Iss 5, Pp 483-487 (2016)
Clinical Endoscopy
ISSN: 2234-2443
2234-2400
Popis: A 34-year-old man was referred to our hospital with gastric polypoid lesions and biopsy-confirmed neuroendocrine tumor (NET). Computed tomography (CT) revealed a 3×3.5×8-cm retroperitoneal mass behind the pancreas, with multiple hepatic metastases. His serum gastrin level was elevated to 1,396 pg/mL. We performed a wedge resection of the stomach, a right hemi-hepatectomy, and a retroperitoneal mass excision. After careful review of the clinical, radiological, histopathological, and immunohistochemical findings, peripancreatic gastrinoma, and synchronous gastric NET were ultimately diagnosed. We reviewed a CT scan that had been performed 6 years previously after surgery for a duodenal perforation. There was no evidence of gastric or hepatic lesions, but the retroperitoneal mass was present at the same site. Had gastrinoma been detected earlier, our patient could have been cured using less invasive treatment. This case demonstrates how important it is to consider Zollinger-Ellison syndrome in patients with a recurrent or aggressive ulcer.
Databáze: OpenAIRE