A High-Fiber Diet May Improve Bowel Function and Health-Related Quality of Life in Patients With Crohn Disease
| Autor: | Carol S. Brotherton, Ann Gill Taylor, Joel G. Anderson, Cheryl Bourguignon |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Dietary Fiber Male medicine.medical_specialty Adolescent Systemic inflammation Gastroenterology Inflammatory bowel disease Article law.invention Crohn Disease Quality of life Randomized controlled trial law Surveys and Questionnaires Internal medicine medicine Humans Single-Blind Method Adverse effect Advanced and Specialized Nursing Gastrointestinal tract Bran business.industry Reproducibility of Results food and beverages Middle Aged medicine.disease C-Reactive Protein Treatment Outcome Quality of Life Feasibility Studies Female medicine.symptom business Gastrointestinal function Biomarkers |
| Zdroj: | Gastroenterology Nursing. 37:206-216 |
| ISSN: | 1042-895X |
| Popis: | Crohn disease is a chronic disorder characterized by episodes of epithelial inflammation in the gastrointestinal tract for which there is no cure. The prevalence of Crohn disease increased in civilized nations during the time period in which food sources were industrialized in those nations. A characteristic of industrialized diets is the conspicuous absence of cereal fiber. The purpose of this 2-group, randomized, controlled study was to investigate the effects of fiber-related dietary instructions specifying wheat bran consumption on health-related quality of life and gastrointestinal function in individuals diagnosed with Crohn disease, as measured by the Inflammatory Bowel Disease Questionnaire and the partial Harvey Bradshaw Index, respectively. Results demonstrated that consuming a wheat bran-inclusive diet was feasible and caused no adverse effects, and participants consuming whole wheat bran in the diet reported improved health-related quality of life (p = .028) and gastrointestinal function (p = .008) compared to the attention control group. The results of a secondary aim, to investigate differences in measures of systemic inflammation, found no group differences in C-reactive protein or erythrocyte sedimentation rates. This study suggests that diet modification may be a welcomed complementary therapy for individuals suffering gastrointestinal disruption associated with Crohn disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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