Molecularly imprinted thin film surfaces in sensing: Chances and challenges
| Autor: | Peter A. Lieberzeit, Christine Unger |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Materials science Microcontact printing Polymers and Plastics In-situ polymer growth General Chemical Engineering 010401 analytical chemistry Molecularly imprinted polymer Nanotechnology 02 engineering and technology General Chemistry Polymer 021001 nanoscience & nanotechnology 01 natural sciences Biochemistry 0104 chemical sciences chemistry Post-polymerization modification Materials Chemistry Environmental Chemistry Surface molecular imprinting Thin film 0210 nano-technology |
| Zdroj: | Reactive and Functional Polymers. 161:104855 |
| ISSN: | 1381-5148 |
| DOI: | 10.1016/j.reactfunctpolym.2021.104855 |
| Popis: | Molecularly imprinted polymers (MIP) claim the potential of replacing biological recognition species, such as antibodies, in sensing. This perspective gives a short overview over current techniques for generating surface imprints in polymers, mainly for bioanalytes. It covers both free radical and controlled radical polymerizations that have been the starting point of research in the field. In the course of time, it has become evident that the quality of surface MIP in general increases when growing the polymer in situ from the respective device surface. This has extended the interest for thin film synthesis to electropolymerizable systems, because they allow for controlling deposition in a comparably precise manner. To increase binding capacities and selectivity, post-polymerization modification of systems has also become a focus of interest. Despite highly appreciable success and substantial progress, questions on reproducibility and potential for mass production still remain open. |
| Databáze: | OpenAIRE |
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