Increased serum delta neutrophil index levels are associated with intrahepatic cholestasis of pregnancy
| Autor: | Nazan Vanlı Tonyalı, Aykan Yucel, Nihal Şahin Uysal, Kemal Sarsmaz, Bahadır Codal, Hasan Eroğlu |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Neutrophils Cholestasis Intrahepatic Gastroenterology Bile Acids and Salts Cholestasis Pregnancy Internal medicine Liver enzyme Inflammatory marker medicine Humans Pregnancy outcomes Retrospective Studies integumentary system Receiver operating characteristic business.industry Curve analysis Infant Newborn Pregnancy Outcome Obstetrics and Gynecology medicine.disease humanities Pregnancy Complications Female business Cholestasis of pregnancy |
| Zdroj: | The journal of obstetrics and gynaecology researchREFERENCES. 47(12) |
| ISSN: | 1447-0756 |
| Popis: | OBJECTIVE This study aims to compare the maternal serum delta neutrophil index (DNI) levels in intrahepatic cholestasis of pregnancy (ICP) and healthy pregnancies. METHODS This study consisted of a group of patients (n = 40) diagnosed with isolated ICP who gave birth in our hospital and a control group (n = 60) between December 1, 2015, and June 30, 2018. The diagnosis of ICP was made based on pruritus and elevated fasting serum bile acids and liver enzymes. Laboratory tests of both groups in the hospitalization process were retrospectively examined. Maternal and neonatal characteristics, pregnancy outcomes, and DNI values of the two groups were compared. Statistical analyses were performed using SPSS version 20. RESULTS Mean maternal serum DNI levels were significantly higher in women with ICP than in the control group (0.49 ± 4.8 vs -3.99 ± 3.02, p = |
| Databáze: | OpenAIRE |
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