Comparison of bentiromide test and rice flour breath hydrogen test in the detection of exocrine pancreatic insufficiency
| Autor: | V P Patel, GeeVarghese Pj, N K Jain, Agarwal N, Capecomorin S. Pitchumoni |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Male medicine.medical_specialty Pancreatic disease Bentiromide Endocrinology Diabetes and Metabolism Rice flour Gastroenterology Endocrinology Internal medicine Internal Medicine medicine para-Aminobenzoates Humans Aminobenzoates False Positive Reactions Exocrine pancreatic insufficiency Bentiromide test Breath test Hepatology medicine.diagnostic_test business.industry Oryza Middle Aged Breath hydrogen test medicine.disease Alcoholism Breath Tests Pancreatitis Exocrine Pancreatic Insufficiency Female business 4-Aminobenzoic Acid medicine.drug Hydrogen |
| Zdroj: | Pancreas. 1(2) |
| ISSN: | 0885-3177 |
| Popis: | Summary Bentiromide test (BT) has been recently approved in the United States for screening patients with chronic pancreatitis for exocrine insufficiency. A few reports have suggested that the rice flour breath hydrogen test (RFBHT)—i.e., breath hydrogen analysis after rice flour ingestion—may also be useful in diagnosing exocrine pancreatic insufficiency. We conducted this study to compare the diagnostic value of these two tests in chronic alcoholic (n = 14) and nutritional or tropical (n = 6) pancreatitis. False-positive results were not noted with either of these two tests in 12 healthy volunteers. BT was positive in 28.6% of patients with chronic alcoholic pancreatitis and in 16.7% of patients with tropical pancreatitis. In comparison, RFBHT was almost twice as sensitive as BT in detecting insufficiency in patients with alcoholic pancreatitis (50 vs. 28.6%) and four times as sensitive in patients with tropical pancreatitis (66.7 vs. 16.7%). Only one patient in our study had a positive BT but a negative RFBHT. We recommend RFBHT as a simple, safe, and inexpensive test in screening patients for exocrine pancreatic insufficiency. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|