Biosynthesis of pyrrolopyrimidines
Autor: | Reid M. McCarty, Vahe Bandarian |
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Rok vydání: | 2012 |
Předmět: |
chemistry.chemical_classification
Purine Guanosine Chemistry Organic Chemistry RNA Structural diversity Biochemistry Article Enzymes chemistry.chemical_compound Pyrimidines Enzyme RNA Transfer Biosynthesis Purines Drug Discovery RNA modification Nucleoside Q Pyrroles Secondary metabolism Purine metabolism human activities Molecular Biology |
Zdroj: | Bioorganic Chemistry. 43:15-25 |
ISSN: | 0045-2068 |
Popis: | Pyrrolopyrimidine containing compounds, also known as 7-deazapurines, are a collection of purine-based metabolites that have been isolated from a variety of biological sources and have diverse functions which range from secondary metabolism to RNA modification. To date, nearly 35 compounds with the common 7-deazapurine core structure have been described. This article will illustrate the structural diversity of these compounds and review the current state of knowledge on the biosynthetic pathways that give rise to them. |
Databáze: | OpenAIRE |
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