Auditing use of antibiotics in Zimbabwean neonates
| Autor: | Valerie J. Robertson, Simbarashe Chimhuya, L. Madzudzo, Gwendoline Chimhini, Michelle Heys, A S Walker, Mike Sharland, Rashida A. Ferrand, Nigel Klein, Felicity Fitzgerald, Caroline Crehan, B. Sado |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Zimbabwe
medicine.medical_specialty medicine.drug_class Antibiotics Short Report Audit Antimicrobial stewardship lcsh:Infectious and parasitic diseases Sepsis 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Neonatal unit lcsh:RC109-216 030212 general & internal medicine Medical prescription Low-income setting Neonatal sepsis business.industry lcsh:Public aspects of medicine lcsh:RA1-1270 Overcrowding Amoxicillin medicine.disease 3. Good health Emergency medicine business medicine.drug |
| Zdroj: | Infection Prevention in Practice Infection Prevention in Practice, Vol 2, Iss 2, Pp-(2020) |
| ISSN: | 2590-0889 |
| Popis: | Summary: Background: Neonatal sepsis is a major cause of morbidity and mortality in low-income settings. As signs of sepsis are non-specific and deterioration precipitous, antibiotics are often used profusely in these settings where diagnostics may not be readily available. Harare Central Hospital, Zimbabwe, delivers 12000 babies per annum admitting ∼4800 to the neonatal unit. Overcrowding, understaffing and rapid staff turnover are consistent problems. Suspected sepsis is highly prevalent, and antibiotics widely used. We audited the impact of training and benchmarking intervention on rationalizing antibiotic prescription using local, World Health Organization-derived, guidelines as the standard. Methods: An initial audit of admission diagnosis and antibiotic use was performed between 8th May - 6th June 2018 as per the audit cycle. An intern training programme, focusing on antimicrobial stewardship and differentiating between babies ‘at risk of’ versus ‘with’ clinically-suspected sepsis was instituted post-primary audit. Re-audit was conducted after 5 months. Results: Sepsis was the most common admitting diagnosis by interns at both time points but reduced at repeat audit (81% versus 59%, P |
| Databáze: | OpenAIRE |
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