Body Mass and Weight Change in Adults in Relation to Mortality Risk
| Autor: | Tamara B. Harris, Demetrius Albanes, Rachel Ballard-Barbash, Victor Kipnis, Albert R. Hollenbeck, Kenneth F. Adams, Michael F. Leitzmann |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Gerontology
Adult Risk Male Adolescent Epidemiology Original Contributions Weight Gain Body Mass Index Cohort Studies Young Adult Weight loss Cause of Death Surveys and Questionnaires medicine Humans Young adult Mortality Letters to the Editor Adiposity Aged business.industry Weight change Hazard ratio Smoking Middle Aged medicine.disease Obesity United States Multivariate Analysis Female medicine.symptom business Weight gain Body mass index Demography Cohort study |
| Popis: | In the midst of an epidemic of obesity, epidemiologists are seeking to establish the relationship of body mass index (BMI; weight (kg)/height (m)(2)) with mortality. In an accompanying article, Adams et al. (Am J Epidemiol. 2014;179(2):135-144) used a subsample of the National Institutes of Health-AARP Diet and Health Study cohort, recruited in 1995-1996 (109,947 people), to examine associations of BMI in early (18 years) and middle (35 and 50 years) adulthood with mortality, as well as the effect of weight gain between these ages on subsequent mortality during 12.5 years' follow-up. They report a positive association between BMI and mortality at each age (using BMI 18.5-22.4 as the referent). Furthermore, there were strong positive associations of weight gain between ages 18 and 35 years and ages 35 and 50 years with mortality. Attainment of a BMI of 25 or higher at a younger age increased risk of death. The findings contrast sharply with those of a recent systematic review and meta-analysis of 97 studies, which found that only the grade 2 and 3 obesity categories (i.e., BMI ≥ 35) were responsible for elevated risk of mortality, with slight protection from overweight (25.0-29.9). Due consideration of the limitations of BMI as a measure of detrimental adiposity and of mortality measures alone to inform clinical practice is indicated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|