Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep
Autor: | Giorgio Bonmassar, Kawin Setsompop, Jonathan R. Polimeni, Laura D. Lewis, Bruce R. Rosen, Robert Stickgold, Nina E. Fultz |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Adult
Male 0301 basic medicine Hemodynamics Electroencephalography Sleep Slow-Wave Article Young Adult 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Neuroimaging Medicine Humans Cerebrospinal Fluid Multidisciplinary medicine.diagnostic_test business.industry Brain Human brain Brain Waves Magnetic Resonance Imaging Electrophysiological Phenomena Electrophysiology 030104 developmental biology medicine.anatomical_structure Delta Rhythm Cerebrovascular Circulation Female Memory consolidation business Sleep Neuroscience 030217 neurology & neurosurgery |
Zdroj: | Science |
Popis: | Fluid dynamics during sleep During non–rapid eye movement sleep, low-frequency oscillations in neural activity support memory consolidation and neuronal computation. Sleep is also associated with increased interstitial fluid volume and clearance of metabolic waste products. It is unknown why these processes co-occur and how they are related. Fultz et al. simultaneously measured electrophysiological, hemodynamic, and flow signals in the human brain (see the Perspective by Grubb and Lauritzen). Large oscillations of fluid inflow to the brain appeared during sleep and were tightly coupled to functional magnetic resonance imaging signals and entrained to electroencephalogram slow waves. Slow oscillatory neuronal activity thus leads to oscillations in blood volume, drawing cerebrospinal fluid into and out of the brain. Science , this issue p. 628 ; see also p. 572 |
Databáze: | OpenAIRE |
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