Usefulness of Reticulocyte Hemoglobin Equivalent in Management of Regular Hemodialysis Patients with Iron Deficiency Anemia
| Autor: | Naomi Niari Dalimunthe, Abdurrahim Rasyid Lubis |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
Reticulocytes endocrine system diseases 030204 cardiovascular system & hematology Hematocrit Gastroenterology Ferric Compounds Cohort Studies Glucaric Acid Hemoglobins iron deficiency 0302 clinical medicine Medicine Prospective Studies Internal medicine Ferric Oxide Saccharated medicine.diagnostic_test Anemia Iron-Deficiency Area under the curve Transferrin reticulocyte Iron deficiency Middle Aged anemia Treatment Outcome Female medicine.drug Adult congenital hereditary and neonatal diseases and abnormalities endocrine system medicine.medical_specialty Anemia Iron sucrose 03 medical and health sciences Renal Dialysis Humans neoplasms business.industry Transferrin saturation medicine.disease RC31-1245 Iron-deficiency anemia ROC Curve Ferritins Hematinics Kidney Failure Chronic Hemoglobin business Biomarkers 030215 immunology |
| Zdroj: | Romanian Journal of Internal Medicine, Vol 54, Iss 1, Pp 31-36 (2016) |
| ISSN: | 1220-4749 |
| Popis: | Introduction. Reticulocyte hemoglobin equivalent (RET-He) is a new parameter for evaluating iron status. This study aims to assess diagnostic value and investigate RET-He as early predictor of response to intravenous iron supplementation. Methods. Seventy-two regular hemodialysis patients at Adam Malik Hospital were studied from April to May 2011. RET-He was compared with conventional iron parameters for identification of iron deficiency. Fifteen patients with iron deficiency anemia were selected to receive 100 mg iron sucrose intravenous during every dialysis session (2x/weeks) for 4 weeks. Results. Receiver operating characteristic (ROC) curve for RET-He revealed the value of area under the curve was 0.818 (p < 0.0001). Using cutoff level 31.65 pg, RET-He showed 81.5% sensitivity and 61.6% specificity. Serum ferritin (r = 0.499, p < 0.0001) and transferrin saturation/ TSAT (r = 0.592, p Conclusion. RET-He is a useful marker of iron deficiency and early predictor of response to intravenous iron supplementation in regular hemodialysis patients. |
| Databáze: | OpenAIRE |
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