Independent self-construal mediates the association between CYP19A1 gene variant and subjective well-being
| Autor: | Xing Yang, Guomin Shen, Mengying Xue, Yafang Yang, Xiaocai Gao, Kejin Zhang, Pengpeng Fang, Pingyuan Gong, Rongjun Yu |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Genotype medicine.drug_class 050109 social psychology Experimental and Cognitive Psychology Personal Satisfaction 050105 experimental psychology Developmental psychology Young Adult Aromatase Arts and Humanities (miscellaneous) Internal medicine Developmental and Educational Psychology medicine Humans Testosterone 0501 psychology and cognitive sciences Big Five personality traits Subjective well-being Association (psychology) Gene Estradiol biology 05 social sciences Self Concept Endocrinology Estrogen biology.protein Female Psychology Personality |
| Zdroj: | Consciousness and Cognition. 55:205-213 |
| ISSN: | 1053-8100 |
| DOI: | 10.1016/j.concog.2017.08.012 |
| Popis: | Testosterone and estrogen are involved in self-related behavioral dispositions and experiences of subjective well-being. In this study, we investigated to what extent the aromatase (CYP19A1) gene, which encodes an enzyme in converting testosterone into estrogen, contributes to subjective well-being and in another self-related disposition: independent and interdependent self-construal. In study 1, a meta-analysis showed that the GG genotype of CYP19A1 (a G/A substitution at Val80, rs700518) was associated with higher testosterone and lower estradiol. In study 2, an empirical study of individuals with the GG (n=115), AG (n=286) and AA (n=193) genotypes indicated that individuals with the GG genotype exhibited higher independent self-construal and higher subjective well-being. The association between the GG genotype of CYP19A1 Val80 and subjective well-being was mediated by the independent self-construal. Our findings reinforce the idea that personality traits such as independent self-construal explain the link between genetic variant and subjective well-being. |
| Databáze: | OpenAIRE |
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