Late spinal cord metastasis of fourth ventricle ependymoma appeared nineteen years after the initial treatment

Autor: Hirokazu Kawano, Tohru Hayashi, Hidenobu Ochiai, Yoshiya Shimao, Yuzo Yamakawa
Rok vydání: 2009
Předmět:
Zdroj: Journal of Neuro-Oncology. 96:295-299
ISSN: 1573-7373
0167-594X
DOI: 10.1007/s11060-009-9964-7
Popis: Spinal cord dissemination (metastasis) of a fourth ventricle ependymoma more than ten years after surgical resection is extremely rare. In this report, we present an unusual case of a fourth ventricle ependymoma with metastasis to the thoracic spinal cord 19 years after the initial therapy, but without local recurrence. A 37 year-old patient underwent gross total resection of a fourth ventricle ependymoma and postoperative radiation therapy to the posterior fossa. Computed tomography (CT) scanning and/or magnetic resonance (MR) imaging performed during follow up examinations, conducted annually for ten years after the therapy, revealed no evidence of local tumor recurrence. However, 19 years after the initial treatment, the patient complained of back pain and gait disturbances. MR imaging revealed an intradural extramedullary tumor at the Th2-5 levels. MR imaging of the brain revealed no local tumor recurrence or intracranial tumor dissemination. Cerebrospinal fluid cytology revealed no presence of tumor cells. Total resection of the spinal cord tumor was performed, and the tumor was diagnosed as an ependymoma. We describe the clinical features of this rare lesion and particularly emphasize the need for long-term follow up, for more than ten years after the initial treatment, in patients with fourth ventricle ependymoma.
Databáze: OpenAIRE
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