Sex differences among users of NSAIDs and opioids during COVID-19 Pandemic

Autor: Roseanne Offiah, Laila Aboulatta, Payam Peymani, Basma Aloud, Kaarina Kowalec, Christine Leong, Joseph Delaney, Jamie Falk, Silvia Alessi-Severini, Sherif Eltonsy
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Clinical Pharmacy. 45:233-239
ISSN: 2210-7711
2210-7703
DOI: 10.1007/s11096-022-01463-y
Popis: Sex-based inequalities in healthcare have been exposed and amplified during the COVID-19 pandemic. However, few studies have reported sex differences in medication utilization and no studies have examined sex differences in prescribed non-steroidal anti-inflammatory drugs (NSAIDs) and opioids utilization.To compare the utilization patterns of prescribed NSAIDs and opioids between males and females in Manitoba, Canada during the COVID-19 pandemic.A cohort of incident and prevalent users of prescribed NSAIDs and opioids was created. Interrupted times series analysis using autoregressive models were used to evaluate the quarterly change in the prevalent and incident users before and after COVID-19 restrictions were applied (first quarter of 2020).COVID-19 restrictions were associated with a significant decrease in the utilization of prescribed NSAIDs and opioids in all users, followed by a revert to the pre-pandemic trends. Among female prevalent and incident NSAIDs users, there was a significant change in trend after COVID-19 restrictions were introduced (βIn this study, a significant sharp decline in the use of prescribed NSAIDs and opioids was shown in both sexes at the onset of the pandemic. However, a significant upward trend is observed in female NSAIDs users as restrictions began to be lifted.
Databáze: OpenAIRE
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