Generalized lymphadenopathy: an unusual presentation of burkitt lymphoma in a Nigerian child: a case report

Autor: Barth F Chukwu, Anthony N Ikefuna, Osita U Ezenwosu, Ifeoma J Emodi, Okechukwu C Okafor
Rok vydání: 2020
Předmět:
Male
medicine.medical_specialty
Antimetabolites
Antineoplastic
Antineoplastic Agents
Hormonal
Prednisolone
030231 tropical medicine
Hepatosplenomegaly
Lymphadenopathy
Nigeria
03 medical and health sciences
0302 clinical medicine
immune system diseases
hemic and lymphatic diseases
Biopsy
medicine
Humans
generalized lymphadenopathy
Child
Antineoplastic Agents
Alkylating
Cyclophosphamide
Immunodeficiency
medicine.diagnostic_test
business.industry
Burkitt lymphoma
Combination chemotherapy
General Medicine
Articles
medicine.disease
Massive lymphadenopathy
Dermatology
Antineoplastic Agents
Phytogenic
Lymphoma
Methotrexate
Treatment Outcome
Burkitt lymphoma
generalized lymphadenopathy
Nigerian child
Vincristine
Nigerian child
Presentation (obstetrics)
medicine.symptom
business
Generalized lymphadenopathy
Zdroj: African Health Sciences
African Health Sciences; Vol 19, No 4 (2019); 3249-3252
ISSN: 1729-0503
1680-6905
Popis: Intoduction: Burkitt Lymphoma is the fastest growing tumor in human and the commonest of the childhood malignancies. Generalized lymphadenopathy is a common feature of immunodeficiency associated Burkitt lymphoma but an uncommon presentation of the endemic type in Human Immunodeficiency Virus (HIV) negative children.Case presentation: The authors report a 6 year old HIV negative boy who presented with generalized lymphadenopathy, cough, weight loss, fever and drenching night sweat and had received native medication as well as treatment in private hospitals. His examination revealed hepatosplenomegaly, bull neck with generalized significant massive lymphadenopathy. Diagnosis was missed initially until a lymphnode biopsy for histology confirmed Burkitt lymphoma. He was managed on combination chemotherapy with complete resolution and now on follow up.Conclusion: To the best of our knowledge, this is the first documented report of its kind of endemic Burkitt lymphoma involving lymphnodes generally as the primary site. High index of suspicion and early biopsy are the key in this uncommon presentation.Keywords: Burkitt lymphoma, generalized lymphadenopathy, Nigerian child.
Databáze: OpenAIRE
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