Generalized lymphadenopathy: an unusual presentation of burkitt lymphoma in a Nigerian child: a case report
Autor: | Barth F Chukwu, Anthony N Ikefuna, Osita U Ezenwosu, Ifeoma J Emodi, Okechukwu C Okafor |
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Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty Antimetabolites Antineoplastic Antineoplastic Agents Hormonal Prednisolone 030231 tropical medicine Hepatosplenomegaly Lymphadenopathy Nigeria 03 medical and health sciences 0302 clinical medicine immune system diseases hemic and lymphatic diseases Biopsy medicine Humans generalized lymphadenopathy Child Antineoplastic Agents Alkylating Cyclophosphamide Immunodeficiency medicine.diagnostic_test business.industry Burkitt lymphoma Combination chemotherapy General Medicine Articles medicine.disease Massive lymphadenopathy Dermatology Antineoplastic Agents Phytogenic Lymphoma Methotrexate Treatment Outcome Burkitt lymphoma generalized lymphadenopathy Nigerian child Vincristine Nigerian child Presentation (obstetrics) medicine.symptom business Generalized lymphadenopathy |
Zdroj: | African Health Sciences African Health Sciences; Vol 19, No 4 (2019); 3249-3252 |
ISSN: | 1729-0503 1680-6905 |
Popis: | Intoduction: Burkitt Lymphoma is the fastest growing tumor in human and the commonest of the childhood malignancies. Generalized lymphadenopathy is a common feature of immunodeficiency associated Burkitt lymphoma but an uncommon presentation of the endemic type in Human Immunodeficiency Virus (HIV) negative children.Case presentation: The authors report a 6 year old HIV negative boy who presented with generalized lymphadenopathy, cough, weight loss, fever and drenching night sweat and had received native medication as well as treatment in private hospitals. His examination revealed hepatosplenomegaly, bull neck with generalized significant massive lymphadenopathy. Diagnosis was missed initially until a lymphnode biopsy for histology confirmed Burkitt lymphoma. He was managed on combination chemotherapy with complete resolution and now on follow up.Conclusion: To the best of our knowledge, this is the first documented report of its kind of endemic Burkitt lymphoma involving lymphnodes generally as the primary site. High index of suspicion and early biopsy are the key in this uncommon presentation.Keywords: Burkitt lymphoma, generalized lymphadenopathy, Nigerian child. |
Databáze: | OpenAIRE |
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