Investigation of desilylation in the recognition mechanism to fluoride by a 1,8-naphthalimide derivative
| Autor: | Gunwoo Kim, Jeeun Woo, Haishi Cao, Hector Palencia, Michael P. Hanrahan, Kevanie Quintero |
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| Rok vydání: | 2014 |
| Předmět: |
Detection limit
Molecular Structure Trimethylsilyl Organic Chemistry Ether Photochemistry Biochemistry Medicinal chemistry Fluorides Naphthalimides chemistry.chemical_compound chemistry Proton NMR Molecule Titration Physical and Theoretical Chemistry Selectivity Derivative (chemistry) Fluorescent Dyes |
| Zdroj: | Org. Biomol. Chem.. 12:8275-8279 |
| ISSN: | 1477-0539 1477-0520 |
| Popis: | A reaction-based chemosensor (AF-1) was designed, synthesized and applied as an optical approach for quantitative measurement of F(-) in MeCN. In the presence of F(-), selective fluoride-assisted desilylation instantly gave colorimetric and fluorogenic signals, providing a dual-optical channel for the detection of F(-). (1)H NMR titration was carried out to investigate the desilylation process, revealing F(-) triggered rapid cleavage of Si-O bond in trimethylsilyl ether. AF-1 exhibited high sensitivity and selectivity to F(-) over other anions. The detection limit to F(-) was calculated to be 0.05 ppm. |
| Databáze: | OpenAIRE |
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