Fish oil feeding lowers thromboxane- and prostacyclin production by rat platelets and aorta and does not result in the formation of prostaglandin I3
| Autor: | F. ten Hoor, D. H. Nugteren, E. Haddeman, G Hornstra, E. Christ-Hazelhof |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty Thromboxane Lipoxygenase Cod Liver Oil Prostaglandin Prostacyclin Biochemistry Muscle Smooth Vascular Thromboxane A2 chemistry.chemical_compound Fish Oils Endocrinology Bleeding time Internal medicine medicine.artery medicine Animals Platelet Aorta medicine.diagnostic_test Chemistry Thromboxanes Rats Inbred Strains Fish oil Epoprostenol Diet Rats Prostaglandin-Endoperoxide Synthases Prostaglandins Helianthus Thromboregulation lipids (amino acids peptides and proteins) Oils medicine.drug |
| Zdroj: | Prostaglandins. 21:727-738 |
| ISSN: | 0090-6980 |
| DOI: | 10.1016/0090-6980(81)90230-6 |
| Popis: | It is demonstrated that feeding cod-liver oil to rats leads to a considerable reduction in the formation of platelet T×A 2 and of vascular PGI 2 . No appreciable formation off T×A 3 and PGI 3 is observed, although arterial thrombosis is depressed and bleeding time is prolonged. These findings contradict the suggested role of prostaglandins of the 3-series in thromboregulation. |
| Databáze: | OpenAIRE |
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