Transient major hypothermia associated with acetaminophen: A pediatric case report and literature review

Autor: N. Chollet, E. Bediou, A.-P. Jonville-Bera, M. Boyer Gervoise, M.-S. Agier
Přispěvatelé: MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques
Rok vydání: 2019
Předmět:
Zdroj: Archives de Pédiatrie
Archives de Pédiatrie, Elsevier, 2019, 26 (6), pp.358-360. ⟨10.1016/j.arcped.2019.06.005⟩
ISSN: 0929-693X
1769-664X
Popis: International audience; We report the case of a 4-month-old baby boy who presented hypothermia (rectal temperature 36° C) after acetaminophen intake for post-vaccination fever. A recurrence of the hypothermia was observed after acetaminophen rechallenge for fever. We reviewed 14 other pediatric cases of hypothermia secondary to therapeutic doses of acetaminophen. Hypothermia after a therapeutic dose is a very rare side effect of acetaminophen. Several hypotheses have been made but the exact mechanism remains unknown.
Databáze: OpenAIRE