The Effects of 660 nm and 780 nm Laser Irradiation on Viability of Random Skin Flap in Rats
| Autor: | Jaqueline de Sousa Crusca, Paulo Sérgio Bossini, Renan Fangel, Vivian Cury, Nivaldo Antonio Parizotto, Ana Claudia Muniz Renno |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Materials science Plastic sheet Biomedical Engineering Skin flap Surgical Flaps law.invention Necrosis Low-Level Light Therapy law medicine Animals Radiology Nuclear Medicine and imaging Irradiation Rats Wistar Skin pathology Skin Tissue Survival Wound Healing business.industry Graft Survival Laser Rats Surgery Disease Models Animal On cells Nuclear medicine business |
| Zdroj: | Photomedicine and Laser Surgery. 27:721-724 |
| ISSN: | 1557-8550 1549-5418 |
| DOI: | 10.1089/pho.2008.2383 |
| Popis: | Some studies have shown that laser phototherapy is able to increase skin flap viability by decreasing the necrotic area and increasing neoangiogenesis. However, the mechanism by which laser acts on cells is not fully understood. The present study investigated the effects of two different laser wavelengths at 30 and 40 J/cm(2) on the viability of skin flap in rats.Sixty male animals were used in this study. They were distributed into the following groups (n = 12 each group): control group, group irradiated with 660 nm at 30 J/cm(2); group irradiated with 780 nm, at 30 J/cm(2), group irradiated with 660 nm at 40 J/cm(2); and group irradiated with 780 nm at 40 J/cm(2). The skin flap was performed on the back of all animals studied, with a plastic sheet interposed between the flap and the donor site. Laser irradiation was done immediately after the surgery and on days 1, 2, 3, and 4 post-surgery. The percentage of the necrotic area of the flap was calculated at day 7 post-surgery.Control group showed a necrotic area of 62.83%. Interestingly, no statistically significant differences were found among the treated groups and the control group.This present study showed that 660 nm and 780 nm lasers at doses of 30 and 40 J/cm(2) were not effective for decreasing the necrotic area of the skin flaps in rats. |
| Databáze: | OpenAIRE |
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