Transcranial Doppler in children with sickle cell disease: Five years of screening experience
| Autor: | Amanda Crow |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Haematology clinic
Pediatrics medicine.medical_specialty Radiological and Ultrasound Technology business.industry Disease medicine.disease Annual Screening Transcranial Doppler Stroke risk Medicine Radiology Nuclear Medicine and imaging Preventative treatment cardiovascular diseases business Review Articles Stroke Cause of death |
| Zdroj: | Australas J Ultrasound Med |
| ISSN: | 2205-0140 1836-6864 |
| DOI: | 10.1002/ajum.12192 |
| Popis: | INTRODUCTION: Sickle cell disease (SCD) is an autosomal recessive, inherited disorder of haemoglobin. Children with sickle cell disease (SCD) are at risk of vascular occlusions. If this occurs in the brain, it can result in stroke. Stroke is the leading cause of death and disability in children with SCD. Transcranial Doppler (TCD) has been shown to accurately predict those children at risk of stroke so appropriate preventative treatment can commence. METHOD: TCD screening with a non‐imaging Doppler machine to assess stroke risk has been in operation at our institution for 5 years. Eighty‐eight patients attending the haematology clinic for SCD are scanned annually. If abnormal velocities are found, repeat scans are performed at close interval to ensure results are reproducible. RESULTS: No child has had a stroke since the start of our screening. Seven of the eighty‐eight patients have shown high velocities on annual screening. CONCLUSION: The introduction of a TCD programme at out institution has identified children at risk of stroke so they can be closely monitored and potentially receive prophylactic treatment. |
| Databáze: | OpenAIRE |
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