Results of second-look resection after primary resection of T1 tumour of the urinary bladder
| Autor: | Staffan Jahnson, Miloš Duchek, Fredrik Wiklund, Sverker Hellsten, Erkki Rintala, Oddvar Mestad, Per-Uno Malmström |
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| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Nephrology medicine.medical_specialty Neoplasm Residual Biopsy Urology Urinary system 030232 urology & nephrology Neoplasms Multiple Primary 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Neoplasm Stage (cooking) Aged Aged 80 and over Bladder cancer Urinary bladder medicine.diagnostic_test business.industry Carcinoma in situ Middle Aged medicine.disease 3. Good health Surgery Treatment Outcome medicine.anatomical_structure Urinary Bladder Neoplasms Second-Look Surgery 030220 oncology & carcinogenesis Female business Carcinoma in Situ Follow-Up Studies |
| Zdroj: | Scandinavian Journal of Urology and Nephrology. 39:206-210 |
| ISSN: | 1651-2065 0036-5599 |
| Popis: | Objective. To study residual tumours at second-look resection in patients resected 4-8 weeks earlier for T1 tumours of the urinary bladder. Material and methods. All patients randomized in the ongoing Nordic T1G2-G3 Bladder Sparing Study with monitored data available were included in the study. Data on residual tumours at second-look resection were compared to basic patient and tumour characteristics. Results. There were 72 patients (56%) without and 57 with residual exophytic tumours. In the former group, 20 patients (28%) had carcinoma in situ, compared to 19 (33%) in the latter group. Potentially dangerous tumours (either carcinoma in situ, T1 or Ta grade 3) were observed in 55 patients (43%). Multiple tumours at primary resection were more prone to residual tumour at second-look resection than single tumours. No other tumour or patient characteristics could predict the occurrence of a residual tumour. Conclusions. Residual tumours are frequently observed at second-look resection 4-8 weeks after primary resection of T1 tumours. The majority of residual tumours detected at this stage are potentially dangerous; therefore, early second-look resection followed by intravesical instillation therapy is mandatory in patients with T1 tumours of the urinary bladder. |
| Databáze: | OpenAIRE |
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