Recent advances in proteolytic stability for peptide, protein, and antibody drug discovery
| Autor: | Xianyin Lai, Mohamed E. H. ElSayed, Jason X. Tang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Drug 0303 health sciences biology Drug discovery media_common.quotation_subject Proteins Peptide 03 medical and health sciences 0302 clinical medicine chemistry Biochemistry Spectrometry Mass Matrix-Assisted Laser Desorption-Ionization 030220 oncology & carcinogenesis Drug Discovery biology.protein Humans Amino acid replacement Antibody Peptides Peptide Hydrolases 030304 developmental biology media_common |
| Zdroj: | Expert Opinion on Drug Discovery. 16:1467-1482 |
| ISSN: | 1746-045X 1746-0441 |
| Popis: | Introduction: To discover and develop a peptide, protein, or antibody into a drug requires overcoming multiple challenges to obtain desired properties. Proteolytic stability is one of the challenge... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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