An Ancient Harappan Genome Lacks Ancestry from Steppe Pastoralists or Iranian Farmers
| Autor: | Nasreen Broomandkhoshbacht, Matthias Meyer, Pranjali Waghmare, Nicole Adamski, Mark Lipson, Matthew Mah, Kumarasamy Thangaraj, Yong Jun Kim, Kristin Stewardson, Vasant Shinde, Malavika Chatterjee, Himani Patel, David Reich, Yogesh Yadav, Avradeep Munshi, Nathan Nakatsuka, Swapan Mallick, Megan Michel, Niraj Rai, Ann Marie Lawson, Amit Kaushik, Matthew Ferry, Nadin Rohland, Vagheesh M. Narasimhan, Amrithavalli Panyam, Nilesh Jadhav, Nick Patterson, Jonas Oppenheimer |
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| Rok vydání: | 2019 |
| Předmět: |
Steppe
media_common.quotation_subject Indus Human Migration Pastoralism Population Biology Iran Southeast asian General Biochemistry Genetics and Molecular Biology Article Lineage (anthropology) Evolution Molecular 03 medical and health sciences 0302 clinical medicine Asian People Humans Pakistan DNA Ancient 030304 developmental biology media_common 0303 health sciences geography Civilization geography.geographical_feature_category Genome Human food and beverages humanities Pedigree Cultural communication Ancient DNA cardiovascular system Ethnology population characteristics 030217 neurology & neurosurgery geographic locations |
| Zdroj: | Cell |
| ISSN: | 1097-4172 |
| Popis: | We report an ancient genome from the Indus Valley Civilization (IVC). The individual we sequenced fits as a mixture of people related to ancient Iranians (the largest component) and Southeast Asian hunter-gatherers, a unique profile that matches ancient DNA from 11 genetic outliers from sites in Iran and Turkmenistan in cultural communication with the IVC. These individuals had little if any Steppe pastoralist-derived ancestry, showing that it was not ubiquitous in northwest South Asia during the IVC as it is today. The Iranian-related ancestry in the IVC derives from a lineage leading to early Iranian farmers, herders, and hunter-gatherers before their ancestors separated, contradicting the hypothesis that the shared ancestry between early Iranians and South Asians reflects a large-scale spread of western Iranian farmers east. Instead, sampled ancient genomes from the Iranian plateau and IVC descend from different groups of hunter-gatherers who began farming without being connected by substantial movement of people. |
| Databáze: | OpenAIRE |
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