Biomarkers of Dietary Exposure Are Associated with Lower Risk of Breast Fibroadenomas in Chinese Women
| Autor: | Dijkstra, S.C., Brouwer, I.A., J.W., Lampe, R.M., Ray, R., Brown, C., Wu, W., Li, C., Chen, I.B., King, D., Goa, Y., Hu, J., Shannon, K., Wahala, D.B., Thomas |
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| Přispěvatelé: | Youth and Lifestyle, Nutrition and Health |
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Medicine (miscellaneous) Physiology proliferative epithelial disorders Lower risk 03 medical and health sciences 0302 clinical medicine Internal medicine Breast Fibroadenoma cancer-risk medicine consumption 030212 general & internal medicine Risk factor skin and connective tissue diseases disease Nutrition and Dietetics Fibrocystic breasts business.industry carotenoids cohort Odds ratio fatty-acids medicine.disease Ascorbic acid Eicosapentaenoic acid Fibroadenoma 3. Good health shanghai body regions Endocrinology 030220 oncology & carcinogenesis epidemiology benign business |
| Zdroj: | The Journal of Nutrition. Oxford University press The Journal of Nutrition, 140(7), 1302-1310 Dijkstra, S C, Brouwer, I A, J.W., L, R.M., R, R., B, C., W, W., L, C., C, I.B., K, D., G, Y., H, J., S, K., W & D.B., T 2010, ' Biomarkers of dietary exposure are associated with lower risk of breast fibroadenomas in Chinese women. ', The Journal of Nutrition . https://doi.org/10.3945/jn.109.119727 The Journal of Nutrition 140 (2010) 7 |
| ISSN: | 0022-3166 |
| Popis: | Fibroadenomas are the most common benign breast condition among women and account for up to 50% of all breast biopsies being performed. Although considered a benign condition, fibroadenomas utilize substantial resources for management and treatment to rule out potential malignancies. Dietary factors may influence benign fibrocystic breast conditions, but little is known of their association with fibroadenomas. We examined possible associations between a broad spectrum of circulating biomarkers of dietary intake and risk of fibroadenomas. Participants were women in a breast self-examination trial in Shanghai, China who were diagnosed with fibroadenomas (n = 258) and 1035 controls. Conditional logistic regression was used to estimate adjusted odds ratios (OR) and 955/0 Cl. Isoflavone concentrations were inversely associated with risk of fibroadenomas. Adjusted OR (95% Cl) for the highest versus the lowest quartile of plasma concentration were 0.36(0.16-0.79; P-trend |
| Databáze: | OpenAIRE |
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